It seems there is mounting evidence that proves chemotherapy causes cancer to spread and yet it is still pushed as the main means of treatment. When will the truth be revealed?
Researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown that the dead and dying cancer cells generated by chemotherapy as well as targeted cancer therapy actually trigger inflammation and this promotes aggressive tumor growth. Their findings were published in the Journal of Experimental Medicine. This team demonstrated that this unintended consequence of cancer treatment can, however, be stopped by resolvins. Resolvins are a family of molecules naturally produced by the body.
According to Newswise, these findings are consistent with clinical observations on radiation-generated debris dating back to the 1950s. Sadly, until now only a few studies have investigated this issue. These same researchers also noted that chemotherapy killed cancer cells to promote growth when a lipid molecule exposed the surface of dead and dying cells triggers the release of cytokines. This, in the end, sets the stage to also promote new tumor growth.
Dipak Panigrahy MD assistant professor of pathology in the Department of Pathology and senior author of this study told Newswise as follows:
“In this study, we demonstrate that chemotherapy-generated debris from dead and dying tumor cells can stimulate tumor growth, which has pivotal implications for the treatment of cancer patients,”
“Conventional cancer therapy designed to kill tumor cells is inherently a double-edged sword.”
“This pro-tumor activity could fuel a positive feedback loop that is difficult to overcome with more aggressive cytotoxic therapy like chemotherapy and radiation,”
“This may explain the inherent therapeutic limit to cancer treatments available today.”
These findings seem to open a door to a potential new more effective approach to preventing reoccurring cancers as well as treatment in general. Adding resolvins might be exactly what we need. While of course, more research will need to be done this is quite interesting and has tons of people thinking.
What do you think about all of this? Could this be as useful in the future as research seems to suggest? I guess only time will tell.
Featured image via Collective Evolution